Summary
Patent Pending CONO1000™ is a clever and powerful, drug-free pain relief support ingredient meant to support your body’s natural ability to provide relief from discomfort. Currently, it is the only natural “Conolidine” ingredient available in the world. It is also used in production of our other patent pending proprietary blend, CONOCB2™.
CONO1000™ is a science backed, phytochemical-rich proprietary blend that can be legally sold across the globe.
This product is a concentrated, naturally occurring herbal compound produced using our patent pending extraction method. Utilizing the Crepe Jasmine plant (Tabernaemontana divaricata), CONO1000™ is meant to support your body’s own ability to clear the way for your naturally occurring “pain killers” (endorphins) to do their job.
CONO1000™ is a safe, potent and natural ingredient, and to date has had no reported or suspected side effects such as those that are commonly attributed to over-the-counter and opioid based, synthetic pain relievers. CONO1000™ is a natural, liquid proprietary blend that can be utilized across multiple Cosmetic, Supplemental (Dietary) and even Over-The-Counter (OTC) applications.
What is Conolidine
Conolidine is widely considered one of the greatest pain relief supporting discoveries in the last 20 years.
It is one of the 66 alkaloids found in the Tabernaemontana divaricata (Crepe Jasmine) plant; generally from the bark and roots of the plant.1 Conolidine has been tested extensively as a pain reliever and has been compared in efficacy to more traditional, opiate-derived pain medications like morphine.
Early scientific opinion surmises that Conolidine is the first known alkaloid to clear the “Scavenger” receptors in your brain, potentially allowing for your body’s natural endorphins to be fully optimized and regulated; a true first of its kind.2 CONO1000™ is the first endorphin-optimizing ingredient ever produced. Studies indicate that each constituent of CONO1000™ possesses none of the detrimental side effects associated with conventional over-the-counter and pharmaceutical prescription pain relief products.
How It Works
CONO1000™ works on the “scavenger receptors” in the brain. Tabernaemontana divaricata (Crepe Jasmine), which contains the Conolidine alkaloid, works on a fairly recently discovered opioid receptor named ACKR3/CXCR7 and regulates naturally produced opioid peptides in the brain
What does that mean? This means that the body’s naturally produced painkillers (opioid peptides) are more capable of reaching your brain’s opioid receptors instead of being “scavenged.”
Conolidine essentially creates a barrier between the “Scavenger” Receptors and Opioid Receptors, allowing your body’s ability to deliver its own endorphins to be fully optimized.
CONO1000™ works on the “scavenger receptors” in the brain. Tabernaemontana divaricata (Crepe Jasmine), which contains the Conolidine alkaloid, works on a fairly recently discovered opioid receptor named ACKR3/CXCR7 and regulates naturally produced opioid peptides in the brain
What does that mean? This means that the body’s naturally produced painkillers (opioid peptides) are more capable of reaching your brain’s opioid receptors instead of being “scavenged.”
Conolidine essentially creates a barrier between the “Scavenger” Receptors and Opioid Receptors, allowing your body’s ability to deliver its own endorphins to be fully optimized.
Route of administration
Oral
When administered orally, CONO1000™ has the potential to work into the body via the mucous membranes in the oral mucosa, as well as the gastrointestinal tract, allowing it to reach the brain and pass through the blood-brain barrier.4 This is possible due to the use of our proprietary extraction method which allows for relatively fast absorption of compounds that may not be generally as effective with standard GI ingestion.
Transdermal
When administered to the skin, CONO1000™ has the potential ability to travel into the bloodstream just as quickly as with oral administration due to the use of the same patent pending extraction technology. Containing industry leading, scientifically studied and natural solvents, transdermal application is thought to be achieved by reversibly decreasing barrier resistance in the skin. Additionally, the ethanolic effect allows the lipid barrier in the skin to be more easily penetrated.
Clinical Studies
Why is CONO1000™ unique?
CONO1000™ is unique in the entirety of its approach, production and science. Completely novel, this ingredient is patent pending and unavailable anywhere else in the world. CONO1000™ has the potential to attack bodily discomfort from a safe, non-addictive and natural space, unlike anything that has preceded it. This ingredient is the first known compound with the potential ability to completely optimize one’s own natural “pain relief system” without the negative effects of traditional pharmaceutical, and over-the-counter, medications. CONO1000™ is a completely drug-free alternative for the potential alleviation of general aches and pains, along with potentially more severe and chronic discomfort.6 CONO1000™ is truly novel, not only in its production technology, which has been known to enhance absorbability, but also with the natural relief support benefits it offers by working with your body’s natural chemistry in a way that has never been seen in the market before.
Ingredients
Tabernaemontana divaricata
full spectrum (Crepe Jasmine) liquid extract